The International Consortium on Agricultural Biotechnology Research (ICABR)
Casein Haplotypes and Their Association with Milk Production Traits in the Holstein Dairy Cattle of Iran
M. Heydarpour , M.R. Nassiri
Department of Animal Science,
College of Agriculture, Ferdowsi University,
Polymorphism of casein genes was studied in half-sib families of artificialinsemination bulls of the Holstein dairy cattle in Iran. Sixteen grandsires and 360 of their sons were genotyped for the following polymorphisms: alpha s1-casein (B, C), beta-casein (A1, A2), the microsatellite within the kappa-casein gene (ms5, ms4) and kappa-casein (A, B, E). Nine different combinations of these alleles, casein haplotypes, were found. Associations between casein haplotypes and milk production traits (milk and protein yield, fat and protein percentage and milking speed) were studied with ordinary least-squares analysis to find a direct effect of the haplotypes or an association within individual grandsire families using the granddaughter design. Estimated breeding values of sons were obtained from cow evaluation by animal model. No direct effect of the casein haplotypes on the traits was found. Within grandsire families, in one out of four families the chromosomal segment characterized by haplotype 3 (B-A2-ms4-A) was associated with an increase in milk yield (P< 0.05) and a decrease in fat percentage (P< 0.05) when contrasted with haplotype 8 (B-A1-ms4-E). The results provide evidence that in the Holstein dairy cattle in Iran at least one quantitative trait locus (QTL) affecting the genetic variation in yields traits is segregating linked to either haplotype 3 (B-A2-ms4-A) or 8 (B-A1-ms4-E).
Key Words: Casein haplotypes, Polymorphism of Casein, Holstein dairy cattle.
|Home Page||Program||Registration||Hotel accommodation||Ravello and surroundings||Social program|